2nd appearance of Deadpool
1st appearance of the New Brotherhood of Evil Mutants
1st appearance of Domino, previously seen in New Mutants #98 impersonated by Copycat
1st team appearance of Weapon P.R.I.M.E.: Weapon X, Rictor, Yeti, Tygerstryke
2nd appearance of the real Domino, previously appeared in X-Force #8
1st team appearance of X-Statix: Coach, Anarchist, Battering Ram, Gin Genie, La Nuit, Plazm, Sluk, Zeitgeist, Doop and U-Go Girl
1st appearance of Dead Girl, a mutant whose powers manifested after she died
